Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600746 | 0.82 | CYP3A4 (0.43) | LMNAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8603411 | 0.79 | RHEB (0.42) | MAOADYRK1AALDH1A1MEN1KMT2A | |
| SCHEMBL8603563 | 0.79 | PARP1 (0.39) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1607615 | 0.77 | MEN1 (0.55) | MAOADYRK1AALDH1A1MEN1KMT2A | |
| SCHEMBL8603460 | 0.76 | KMT2A (0.58) | DYRK1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8600706 | 0.75 | FEN1 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8599590 | 0.75 | MAOA (0.40) | MAOAKMT2APOLB | |
| SCHEMBL8604181 | 0.75 | HTR1A (0.46) | LMNATP53ALDH1A1KDM4E | |
| SCHEMBL8602835 | 0.75 | HTR1A (0.46) | LMNATP53ALDH1A1KDM4E | |
| SCHEMBL3149877 | 0.74 | USP2 (0.50) | MAOALMNATP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |