Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.35 |
| ▸ | MMP12 | P39900 | 5/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600219 | 0.82 | MAOA (0.43) | ALDH1A1CA2MEN1KMT2AKDM4E | |
| SCHEMBL28806403 | 0.76 | PBRM1 (0.50) | CYP3A4ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL8603411 | 0.76 | RHEB (0.42) | ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL8600177 | 0.73 | MAOA (0.46) | CYP3A4ALDH1A1ENPP2RAB9ANPC1 | |
| SCHEMBL7390868 | 0.72 | LMNA (0.47) | CYP3A4ALDH1A1CA2RAB9ANPC1 | |
| SCHEMBL8603563 | 0.72 | PARP1 (0.39) | CYP3A4ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL11457868 | 0.70 | ALDH1A1 (0.54) | ALDH1A1ENPP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8603706 | 0.70 | TYR (0.53) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL8600706 | 0.69 | FEN1 (0.43) | CYP3A4ALDH1A1MEN1KMT2AIDH1 | |
| SCHEMBL132773 | 0.69 | ALDH1A1 (0.78) | CYP3A4ALDH1A1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |