Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 8/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626740 | 0.81 | TXNRD1 (0.39) | TXNRD1GSRVCAM1ALDH1A1MAPT | |
| SCHEMBL8596415 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL2362856 | 0.78 | TXNRD1 (0.54) | TXNRD1GSRGSTP1ALDH1A1MEN1 | |
| SCHEMBL9453001 | 0.78 | TXNRD1 (0.54) | TXNRD1GSRGSTP1ALDH1A1MEN1 | |
| SCHEMBL5700184 | 0.76 | KMT2A (0.43) | TXNRD1VCAM1ALDH1A1MAPTMEN1 | |
| SCHEMBL8598731 | 0.74 | ALDH1A1 (0.40) | TXNRD1ALDH1A1XDHMAPTMEN1 | |
| SCHEMBL7033755 | 0.74 | TXNRD1 (0.60) | TXNRD1GSRGSTP1VCAM1MAPT | |
| SCHEMBL8600910 | 0.74 | TXNRD1 (0.41) | TXNRD1GSRGSTP1VCAM1ALDH1A1 | |
| SCHEMBL18497232 | 0.74 | TXNRD1 (0.56) | TXNRD1GSRGSTP1VCAM1ALDH1A1 | |
| SCHEMBL8595791 | 0.74 | TDP1 (0.42) | TXNRD1GSRALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |