Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600265 | 0.81 | TXNRD1 (0.51) | TXNRD1SMN1; SMN2GSRMAPTPOLB | |
| SCHEMBL8716642 | 0.81 | KMT2A (0.51) | HPGDPOLBPKMCYP19A1CA1 | |
| SCHEMBL8713770 | 0.80 | KMT2A (0.50) | TXNRD1ESR1RECQLGLAHPGD | |
| SCHEMBL8711803 | 0.80 | KMT2A (0.50) | TXNRD1ESR1RECQLGLAHPGD | |
| SCHEMBL8711023 | 0.80 | KMT2A (0.50) | TXNRD1ESR1RECQLGLAHPGD | |
| SCHEMBL8711063 | 0.80 | KMT2A (0.50) | TXNRD1ESR1RECQLGLAHPGD | |
| SCHEMBL10792789 | 0.80 | KMT2A (0.50) | TXNRD1ESR1RECQLGLAHPGD | |
| SCHEMBL8596415 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2LMNARECQLTSHRMAPK1 | |
| SCHEMBL8595772 | 0.78 | LMNA (0.50) | SMN1; SMN2LMNAMAPTRECQLMAPK1 | |
| SCHEMBL8710708 | 0.76 | KMT2A (0.53) | RECQLHPGDPOLBPKMCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |