SCHEMBL860028

SCHEMBL860028

O=C(O)/C=C(/CCC(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
KDM4E B2RXH2 3/20 0.61
LMNA P02545 4/20 0.47
EGLN1 Q9GZT9 3/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
MAPK1 P28482 1/20 0.43
SLC13A3 Q8WWT9 1/20 0.43
OR51E2 Q9H255 1/20 0.43
SLC15A2 Q16348 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.36
PHF8 Q9UPP1 3/20 0.36
KDM2A Q9Y2K7 3/20 0.36
NFKB1 P19838 2/20 0.35
PMP22 Q01453 1/20 0.35
KDM5C P41229 2/20 0.35
KDM6B O15054 1/20 0.35
FOLH1 Q04609 1/20 0.35
GABRR1 P24046 1/20 0.35
FFAR3 O14843 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860029 1.00 TSHR (0.61) TSHRKDM4ELMNAEGLN1ALKBH5
SCHEMBL19407225 1.00 TSHR (0.61) TSHRKDM4ELMNAEGLN1ALKBH5
SCHEMBL28488698 0.92 TSHR (0.62) TSHRKDM4ELMNAEGLN1ALKBH5
SCHEMBL10052700 0.85 TSHR (0.56) TSHRKDM4ELMNASLC22A6NFKB1
SCHEMBL10052694 0.85 TSHR (0.56) TSHRKDM4ELMNAEGLN1ALKBH5
SCHEMBL10932417 0.81 TSHR (0.56) TSHRKDM4ELMNASLC22A6NFKB1
SCHEMBL30461024 0.80 KDM4E (0.44) TSHRKDM4ELMNAEGLN1ALKBH5
SCHEMBL15871668 0.80 LMNA (0.43) TSHRKDM4ELMNAEGLN1ALKBH5
SCHEMBL19745932 0.79 TSHR (0.54) TSHRKDM4ELMNAOR51E2SLC22A6
SCHEMBL4532099 0.79 KDM4E (0.54) TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111743783-B Double-paste type dental resin reinforced glass ion water-gate composition 株式会社松风 2024-04-16 CN claimed
CN-117357405-A Dental adhesive glass ion water-gate composition with good removability 株式会社松风 2024-01-09 CN claimed
CN-116942885-A Self-expanding medical suture and preparation method thereof 海南百迈科医疗科技股份有限公司 2023-10-27 CN claimed
CN-113667336-A UV gloss oil for printing and preparation method thereof 朗升柯式印刷(深圳)有限公司 2021-11-19 CN claimed
US-10987283-B2 Dental glass ionomer cement composition for luting excellent in removability SHOFU INC. (JP) 2021-04-27 US claimed
EP-3552596-A2 SS IONOMER CEMENT COMPOSITION FOR DENTAL LUTING CEMENTS Shofu Inc. (JP) 2019-10-16 EP claimed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-12552956-B2 Photopolymerizable type dental surface coating composition SHOFU INC. (JP) 2026-02-17 US disclosed
EP-4659729-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-12-10 EP disclosed
US-20250367080-A1 DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2025-12-04 US disclosed
EP-4635469-A1 DENTAL GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-10-22 EP disclosed
US-20250195339-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2025-06-19 US disclosed
EP-2434421-A2 Compositions and methods for modeling saccharomyces cerevisiae metabolism The Regents of The University of California (US) 2012-03-28 EP disclosed
US-20120028320-A1 PREPARATION OF ADIPIC ACID DSM IP ASSETS B.V. (NL) 2012-02-02 US disclosed
US-20100280803-A1 Compositions and Methods for Modeling Saccharomyces cerevisiae Metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2010-11-04 US disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
US-7751981-B2 Articles of manufacture and methods for modeling Saccharomyces cerevisiae metabolism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-06 US disclosed
US-20080164050-A1 Regular Square Insulating Cable, Application of Such Regular Square Insulating Cable and Method for Manufacturing Such Regular Square Insulating Cable MITSUBISHI CABLE INDUSTRIES, LTD. (JP) 2008-07-10 US disclosed
EP-1858030-A1 REGULAR SQUARE INSULATING CABLE, APPLICATION OF SUCH REGULAR SQUARE INSULATING CABLE AND METHOD FOR MANUFACTURING SUCH REGULAR SQUARE INSULATING CABLE Mitsubishi Cable Industries, Ltd. (JP) 2007-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 TSHR 3161/4885KDM4E 2270/4885LMNA 3276/4885
US-12552956-B2 Photopolymerizable type dental surface coating composition CDH1, DCLRE1A, ITGA1 TSHR 3987/4885KDM4E 98/4885LMNA 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.