Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595237 | 0.83 | HCAR2 (0.34) | ALDH1A1LMNAACHETSHRTDP1 | |
| SCHEMBL8597058 | 0.83 | ALDH1A1 (0.39) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL8598772 | 0.80 | ALDH1A1 (0.45) | ALDH1A1LMNAACHESMN1; SMN2TSHR | |
| SCHEMBL8600469 | 0.79 | ACHE (0.45) | ALDH1A1ACHEHTTSMN1; SMN2KMT2A | |
| SCHEMBL8860602 | 0.79 | MAPT (0.39) | ACHEMAPT | |
| SCHEMBL8599805 | 0.78 | ALDH1A1 (0.34) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL14715925 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL20473345 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL3407387 | 0.74 | ALDH1A1 (0.34) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL8599647 | 0.74 | CES2 (0.42) | HSD17B10TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592669-B1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5665270-A | Optically active trifluorolactic acid derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0592669-A1 | OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1994-04-20 | — | — | EP | disclosed |