Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763018 | 0.80 | CYP1A2 (0.37) | CYP1A2 | |
| SCHEMBL8762979 | 0.80 | FKBP1A (0.32) | KCNH3CYP1A2 | |
| SCHEMBL5599002 | 0.80 | — | — | |
| SCHEMBL3598980 | 0.79 | ALDH1A1 (0.35) | MAPK1 | |
| SCHEMBL6713075 | 0.78 | KCNH3 (0.31) | KCNH3CYP1A2 | |
| SCHEMBL20715353 | 0.78 | — | — | |
| SCHEMBL29152239 | 0.78 | — | — | |
| SCHEMBL576482 | 0.78 | — | — | |
| SCHEMBL6256848 | 0.77 | KCNH3 (0.33) | KCNH3CYP1A2 | |
| SCHEMBL8763009 | 0.76 | KDM4E (0.36) | CYP1A2CYP2C9MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584663-B1 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF AG (DE) | 1998-02-25 | — | — | EP | claimed |
| US-5466831-A | Preparation of 3-(2-acyloxyethyl)-dihydro-2(3H)furanones | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-14 | — | — | US | claimed |
| US-5371246-A | Preparation of tetrahydropyran-4-carboxylic acid and esters thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | claimed |
| EP-0584663-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | claimed |
| EP-0584663-B1 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| EP-0584631-B1 | Process of preparing 3-(2'-acyloxyethyl)-dihydro-2(3H)furanones | BASF AG (DE) | 1997-07-16 | — | — | EP | disclosed |
| US-5580994-A | Preparation of tetrahydropyran-4-carboxylic acid and its esters | BASF AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| EP-0678091-B1 | METHOD OF PREPARING TETRAHYDROPYRAN-4-CARBOXYLIC ACID AND ITS ESTERS | BASF AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| US-5466831-A | Preparation of 3-(2-acyloxyethyl)-dihydro-2(3H)furanones | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0678091-A1 | METHOD OF PREPARING TETRAHYDROPYRAN-4-CARBOXYLIC ACID AND ITS ESTERS. | BASF AG (DE) | 1995-10-25 | — | — | EP | disclosed |
| US-5371246-A | Preparation of tetrahydropyran-4-carboxylic acid and esters thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| WO-1994015931-A1 | METHOD OF PREPARING TETRAHYDROPYRAN-4-CARBOXYLIC ACID AND ITS ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1994-07-21 | — | — | WO | disclosed |
| EP-0584663-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584631-A1 | Process of preparing 3-(2'-acyloxyethyl)-dihydro-2(3H)furanones | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | disclosed |