Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645517 | 0.89 | FKBP1A (0.35) | ALDH1A1KDM4EHPGDHSD17B10MTNR1A | |
| SCHEMBL11368930 | 0.88 | MTNR1A (0.40) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL11369090 | 0.88 | MTNR1A (0.40) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL14341641 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8763009 | 0.84 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL7657725 | 0.83 | NLRP3 (0.41) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL14341640 | 0.80 | TSHR (0.41) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL14489286 | 0.79 | FKBP1A (0.43) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8600478 | 0.79 | POLB (0.34) | MAPK1 | |
| SCHEMBL9298152 | 0.78 | PDE4D (0.35) | ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994112-B1 | Method for separating contaminants from 3-(2'-acetoxy-ethyl)-dihydro-2(3h)furanone | BASF AG (DE) | 2002-07-24 | — | — | EP | claimed |
| EP-1037884-B1 | METHOD FOR SEPARATING CONTAMINANTS FROM 3-(2'-ACETOXY-ETHYL-DIHYDRO-2(3H)FURANONE | BASF AG (DE) | 2002-03-13 | — | — | EP | claimed |
| US-6201135-B1 | PREPARING 3-(2'-ACETOXYETHYL)DIHYDRO-2(3H)-FURANONE CONTAINING UNDESIRABLE IMPURITIES IN A MANNER KNOWN PER SE BY ACETYLATING 3-(2'-HYDROXYETHYL)-DIHYDRO-2-(3H)-FURANONE, TREATING IT WITH STRONG MINERAL ACIDS, REMOVING DECOMPOSITION PRODUCTS | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | claimed |
| CN-1281445-A | Method for removing impurities in 3- (2' -acetoxyethyl) dihydro-2 (3H) -furanone | BASF AG (DE) | 2001-01-24 | — | — | CN | claimed |
| EP-0994112-A1 | Method for separating contaminants from 3-(2'-acetoxy-ethyl)-dihydro-2(3h)furanone | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-19 | — | — | EP | claimed |
| EP-0584663-B1 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF AG (DE) | 1998-02-25 | — | — | EP | claimed |
| US-5371246-A | Preparation of tetrahydropyran-4-carboxylic acid and esters thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | claimed |
| EP-0584663-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | claimed |
| US-20100105929-A1 | PROCESS FOR THE PREPARATION OF y-BUTYROLACTONES | LONZA LTD. (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-2079720-A1 | PROCESS FOR THE PREPARATION OF GAMMA-BUTYROLACTONES | LONZA AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| EP-1911752-A1 | Process for the preparation of butyrolactones | LONZA AG (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2008040530-A1 | PROCESS FOR THE PREPARATION OF γ-BUTYROLACTONES | LONZA AG (CH) | 2008-04-10 | — | — | WO | disclosed |
| US-6488818-B1 | DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | disclosed |
| US-6488818-B1 | DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | disclosed |
| EP-0588224-A1 | Process for the preparation of 3-(2'-oxyethyl)-dihydro-2-(3H)furanones | BASF Aktiengesellschaft (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0584663-A2 | Process for the preparation of tetrahydropyran-4-carboxylic acid and his esters | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0584631-A1 | Process of preparing 3-(2'-acyloxyethyl)-dihydro-2(3H)furanones | BASF Aktiengesellschaft (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0246581-B1 | PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED GAMMA-BUTYROLACTONES | BASF Aktiengesellschaft (DE) | 1991-10-09 | — | — | EP | disclosed |
| US-4831166-A | REACTING ALKYLENE OXIDE WITH ACYLACETATE USING IONIC HALIDE CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0246581-A2 | Process for the preparation of alpha-substituted gamma-butyrolactones | BASF Aktiengesellschaft (DE) | 1987-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105929-A1 | PROCESS FOR THE PREPARATION OF y-BUTYROLACTONES | CYP17A1, HSD17B7, CYP19A1 | ALDH1A1 1212/4885KDM4E 219/4885HPGD 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.