Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601525 | 0.82 | KMT2A (0.36) | TSHRMAPK1HIF1ASMN1; SMN2CA12 | |
| SCHEMBL8597357 | 0.82 | ALDH1A1 (0.39) | TSHRMAPK1HIF1ACA12ALDH1A1 | |
| SCHEMBL8602563 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8563864 | 0.79 | NSD2 (0.49) | SMN1; SMN2CA12CA9KDM4ECYP1A2 | |
| SCHEMBL8628187 | 0.78 | CA12 (0.35) | CA12CA1CA2CA9 | |
| SCHEMBL8596152 | 0.78 | RECQL (0.43) | TSHRMAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL8598890 | 0.77 | TSHR (0.34) | TSHRMAPK1HIF1ASMN1; SMN2CA12 | |
| SCHEMBL8600588 | 0.77 | KDM4E (0.38) | TSHRMEN1KMT2AKDM4EMAPT | |
| SCHEMBL8596102 | 0.76 | HCAR3 (0.42) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL8599491 | 0.74 | HIF1A (0.39) | TSHRMAPK1HIF1ASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |