Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598219 | 0.83 | RECQL (0.43) | RECQLCA12CA9TSHRMEN1 | |
| SCHEMBL8599314 | 0.82 | RECQL (0.51) | RECQLCA12CA9TSHRMEN1 | |
| SCHEMBL8596657 | 0.81 | TXNRD1 (0.43) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8628083 | 0.79 | CYP19A1 (0.37) | RECQLCA12CA9TSHRSMN1; SMN2 | |
| SCHEMBL8601240 | 0.78 | RECQL (0.40) | RECQLCA12CA9TSHRMEN1 | |
| SCHEMBL8600670 | 0.78 | TSHR (0.34) | CA12CA9TSHRMEN1KMT2A | |
| SCHEMBL8598700 | 0.77 | HCAR3 (0.44) | TP53TDP1POLBHTTSMN1; SMN2 | |
| SCHEMBL8563864 | 0.77 | NSD2 (0.49) | CA12CA9CYP1A2CYP3A4POLB | |
| SCHEMBL8597463 | 0.76 | HTT (0.39) | RECQLCA12CA9TSHRMEN1 | |
| SCHEMBL8598258 | 0.75 | L3MBTL1 (0.47) | RECQLCA12CA9TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |