Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.44 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563598 | 0.83 | LMNA (0.55) | NSD2LMNACYP19A1POLBVCAM1 | |
| SCHEMBL8561895 | 0.82 | HTT (0.52) | NSD2LMNACYP19A1POLBVCAM1 | |
| SCHEMBL8562148 | 0.81 | ALDH1A1 (0.48) | LMNAPOLBSMN1; SMN2KDM4ECA9 | |
| SCHEMBL8563126 | 0.79 | CYP19A1 (0.50) | NSD2LMNACYP19A1POLBVCAM1 | |
| SCHEMBL8600670 | 0.79 | TSHR (0.34) | LMNACYP19A1SMN1; SMN2KDM4ECA12 | |
| SCHEMBL8568477 | 0.79 | KMT2A (0.44) | CYP19A1POLBCA12CA9ATM | |
| SCHEMBL8596152 | 0.77 | RECQL (0.43) | LMNAPOLBSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL8562887 | 0.76 | BACE1 (0.52) | LMNAPOLBSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL8567834 | 0.75 | POLB (0.48) | NSD2LMNACYP19A1POLBVCAM1 | |
| SCHEMBL8567841 | 0.75 | CYP19A1 (0.57) | NSD2LMNACYP19A1POLBVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |