Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599984 | 0.79 | MEN1 (0.55) | MEN1KMT2ARAB9APAX8MAPT | |
| SCHEMBL8567910 | 0.78 | RAB9A (0.58) | MEN1KMT2ARAB9APAX8MAPT | |
| SCHEMBL8597357 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8600198 | 0.77 | MAPT (0.58) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL357662 | 0.77 | CYP19A1 (0.59) | MEN1KMT2AALDH1A1HTT | |
| SCHEMBL11107368 | 0.77 | MEN1 (0.59) | MEN1KMT2ARAB9APAX8MAPT | |
| SCHEMBL28332934 | 0.77 | MEN1 (0.59) | MEN1KMT2ARAB9APAX8MAPT | |
| SCHEMBL8595936 | 0.76 | PAX8 (0.50) | MEN1KMT2ARAB9APAX8MAPT | |
| SCHEMBL8599491 | 0.76 | HIF1A (0.39) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL8630082 | 0.76 | MEN1 (0.51) | MEN1KMT2ARAB9APAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |