Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.51 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563877 | 0.79 | TXNRD1 (0.63) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4504076 | 0.79 | CYP19A1 (0.83) | MEN1KMT2AVCAM1CYP19A1LMNA | |
| SCHEMBL8563598 | 0.78 | LMNA (0.55) | KMT2AVCAM1CYP19A1LMNAALDH1A1 | |
| SCHEMBL8600832 | 0.78 | MEN1 (0.51) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8567834 | 0.78 | POLB (0.48) | VCAM1CYP19A1LMNAMAPTKEAP1 | |
| SCHEMBL11107368 | 0.77 | MEN1 (0.59) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28332927 | 0.77 | TXNRD1 (0.60) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8595936 | 0.76 | PAX8 (0.50) | RAB9AMEN1KMT2ALMNAMAPT | |
| SCHEMBL8566453 | 0.76 | MEN1 (0.58) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28331489 | 0.75 | TXNRD1 (0.62) | RAB9AMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |