Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564291 | 0.82 | MAPT (0.49) | TDP1LMNAL3MBTL1SMN1; SMN2CYP2C9 | |
| SCHEMBL8600860 | 0.80 | DHFR (0.41) | TDP1DHFRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8597429 | 0.78 | RXFP1 (0.40) | TDP1LMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL8598680 | 0.78 | MAPT (0.38) | TDP1LMNASMN1; SMN2CYP3A4RAB9A | |
| SCHEMBL8597358 | 0.78 | DHFR (0.41) | TDP1DHFRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL8597788 | 0.75 | GSK3A (0.46) | LMNASMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL8599095 | 0.75 | ALDH1A1 (0.37) | TDP1LMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL8595032 | 0.74 | MAPT (0.40) | TDP1LMNAL3MBTL1SMN1; SMN2CYP3A4 | |
| SCHEMBL8625911 | 0.74 | MAPT (0.35) | TDP1LMNASMN1; SMN2CYP3A4RAB9A | |
| SCHEMBL8564301 | 0.73 | KDM4E (0.47) | TDP1LMNAL3MBTL1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |