Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723480 | 0.85 | ALDH1A1 (0.48) | KMT2ALMNAMEN1ALDH1A1HTT | |
| SCHEMBL8600883 | 0.80 | LMNA (0.46) | KMT2ALMNAMEN1KDM4EALDH1A1 | |
| SCHEMBL1423557 | 0.80 | EGLN2 (0.60) | NAAAHPGDALOX12KDM4EHTT | |
| SCHEMBL31500526 | 0.80 | NAAA (0.52) | NAAALMNAHPGDALOX12KDM4E | |
| SCHEMBL8597516 | 0.80 | HTT (0.52) | NAAALMNAHPGDALOX12KDM4E | |
| SCHEMBL8778065 | 0.79 | LMNA (0.52) | KMT2ALMNAMEN1TP53HSP90AA1 | |
| SCHEMBL1423213 | 0.79 | NAAA (0.51) | NAAAHPGDALOX12KDM4EHTT | |
| SCHEMBL14284344 | 0.79 | NAAA (0.61) | NAAAHPGDALOX12KDM4EHTT | |
| SCHEMBL9626697 | 0.79 | NAAA (0.61) | NAAAHPGDALOX12KDM4EHTT | |
| SCHEMBL9967355 | 0.79 | NAAA (0.55) | NAAALMNAHPGDALOX12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |