Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629232 | 0.88 | FFAR1 (0.50) | APPFFAR1GABRPGABRDGABRA1 | |
| SCHEMBL6653836 | 0.79 | APP (0.53) | APPFFAR1GABRPGABRDGABRA1 | |
| SCHEMBL68968 | 0.78 | NPSR1 (0.59) | APPFFAR1NPSR1VCPFFAR4 | |
| Benzene SCHEMBL28174766 | 0.78 | NPSR1 (0.59) | APPFFAR1NPSR1VCPFFAR4 | |
| SCHEMBL670335 | 0.77 | VCP (0.58) | FFAR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3151444 | 0.77 | FFAR1 (0.52) | APPFFAR1GABRPGABRDGABRA1 | |
| SCHEMBL7118049 | 0.77 | GSK3B (0.48) | FFAR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4149218 | 0.77 | FFAR1 (0.44) | FFAR1GABRPGABRDGABRA1GABRB1 | |
| Guanidine SCHEMBL10490342 | 0.77 | FFAR1 (0.44) | APPFFAR1GABRPGABRDGABRA1 | |
| SCHEMBL2636129 | 0.77 | TSHR (0.44) | FFAR1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821677-A1 | OXAZOLINE AND THIAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033180-A1 | OXAZOLINE AND THIAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-24 | — | — | WO | disclosed |