Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794117 | 0.98 | TSHR (0.43) | TSHRALOX15FFAR1PTGDR2GABRP | |
| SCHEMBL3858463 | 0.94 | FFAR1 (0.44) | TSHRALOX15FFAR1PTGDR2GABRP | |
| Guanidine SCHEMBL2281423 | 0.90 | LMNA (0.39) | TSHRALOX15FFAR1PTGDR2GABRP | |
| SCHEMBL9629232 | 0.88 | FFAR1 (0.50) | FFAR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8443823 | 0.82 | KCNH2 (0.42) | TSHRALOX15PTGDR2CES2CES1 | |
| SCHEMBL4487823 | 0.80 | ACACB (0.46) | TSHRALOX15FFAR1PTGDR2CES2 | |
| SCHEMBL6774688 | 0.80 | NPC1 (0.42) | TSHRALOX15PTGDR2CES2CES1 | |
| SCHEMBL11808810 | 0.79 | PTGDR2 (0.36) | TSHRFFAR1PTGDR2GABRPGABRD | |
| SCHEMBL11808795 | 0.79 | S100A4 (0.42) | TSHRFFAR1PTGDR2SRD5A2 | |
| SCHEMBL6653836 | 0.79 | APP (0.53) | FFAR1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113548965-B | Preparation method of 1,4 eneyne compound | 南京工业大学 | 2022-07-26 | — | — | CN | claimed |
| CN-113548965-A | Preparation method of 1, 4-eneyne compound | 南京工业大学 | 2021-10-26 | — | — | CN | claimed |
| EP-1153024-B1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2004-04-28 | — | — | EP | claimed |
| JP-2002537300-A | — | — | 2002-11-05 | — | — | JP | claimed |
| US-20020016329-A1 | 2-Amino-6-anilino-purines and their use as medicaments | NOVARTIS AG (CH) | 2002-02-07 | — | — | US | claimed |
| EP-1153024-A1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | Novartis AG (CH) | 2001-11-14 | — | — | EP | claimed |
| WO-2000049018-A1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | claimed |
| CN-122059959-A | Synthesis method and application of pyrrolo [2,1-a ] isoquinoline compound | 河南工业大学 | 2026-05-19 | — | — | CN | disclosed |
| US-12404265-B2 | Substituted pyridine derivatives as SARM1 inhibitors | NURA BIO, INC. (US) | 2025-09-02 | — | — | US | disclosed |
| US-20240166662-A1 | THIOPHENE BASED COMPOUNDS AND USE THEREOF AS BCKDK INHIBITORS | Ramino-Bio Ltd. (IL) | 2024-05-23 | — | — | US | disclosed |
| US-11970481-B1 | Substituted pyridine derivatives as SARM1 inhibitors | NURA BIO, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| US-20240116901-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. | 2024-04-11 | — | — | US | disclosed |
| EP-3953360-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | HOFFMANN LA ROCHE (CH) | 2024-02-28 | — | — | EP | disclosed |
| EP-0663401-A1 | MORPHINAN DERIVATIVE AND MEDICINAL USE | TORAY INDUSTRIES, INC. (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0123908-B1 | HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-10-14 | — | — | EP | disclosed |
| EP-0123937-B1 | A BASE PRECURSOR FOR HEAT-DEVELOPABLE PHOTOSENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |
| US-4560763-A | ALKYNYL CARBOXYLIC ACID SALT OF ORGANIC BASE | FUJI PHOTO FILM CO., LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| US-4499172-A | Heat-developable color light-sensitive material with alkyl carboxylic acid base precursor containing triple bond | FUJI PHOTO FILM CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| EP-0123908-A2 | Heat-developable color light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |
| EP-0123937-A1 | A base precursor for heat-developable photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404265-B2 | Substituted pyridine derivatives as SARM1 inhibitors | SARM1, SARNP, ADRM1 | TSHR 4223/4885ALOX15 4299/4885FFAR1 4246/4885 |
| US-20020016329-A1 | 2-Amino-6-anilino-purines and their use as medicaments | CDK14, CDK1, CCNB1 | TSHR 4550/4885ALOX15 3352/4885FFAR1 4790/4885 |
| US-11970481-B1 | Substituted pyridine derivatives as SARM1 inhibitors | SARM1, SARNP, ADRM1 | TSHR 4223/4885ALOX15 4299/4885FFAR1 4246/4885 |
| US-20240116901-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | SARM1, SARNP, ADRM1 | TSHR 4223/4885ALOX15 4299/4885FFAR1 4246/4885 |
| US-20240166662-A1 | THIOPHENE BASED COMPOUNDS AND USE THEREOF AS BCKDK INHIBITORS | BCKDK, BCAT2, BCAT1 | TSHR 3563/4885ALOX15 3385/4885FFAR1 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.