SCHEMBL8601232

SCHEMBL8601232

CCC(C)COc1cc(N=C=S)c(F)cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8602412 0.84 PPOX (0.38)
SCHEMBL8598170 0.82 DHODH (0.35)
SCHEMBL8599225 0.81 PPOX (0.40)
SCHEMBL8600619 0.81 SMN1; SMN2 (0.42)
SCHEMBL8603664 0.79 SMN1; SMN2 (0.40)
SCHEMBL8579591 0.78 PPOX (0.38)
SCHEMBL8602477 0.78 MAPT (0.42)
SCHEMBL8603005 0.77 NR1I2 (0.39)
SCHEMBL8602400 0.77 DHODH (0.32)
SCHEMBL7535311 0.76 NPC1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626370-B1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL CO (JP) 1998-02-11 EP disclosed
EP-0626370-A1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-11-30 EP disclosed