Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | BLK | P51451 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603664 | 0.97 | SMN1; SMN2 (0.40) | SMN1; SMN2GLAHTTRECQLBACE1 | |
| SCHEMBL8599225 | 0.94 | PPOX (0.40) | SMN1; SMN2GLAHTTRECQLBACE1 | |
| SCHEMBL8602412 | 0.88 | PPOX (0.38) | SMN1; SMN2PPOXATML3MBTL1ALDH1A1 | |
| SCHEMBL10574907 | 0.87 | GLA (0.41) | SMN1; SMN2GLAHTTRECQLBACE1 | |
| SCHEMBL8599268 | 0.86 | ALDH1A1 (0.56) | SMN1; SMN2HTTRECQLPPOXL3MBTL1 | |
| SCHEMBL8600272 | 0.84 | ALDH1A1 (0.54) | HTTRECQLPPOXL3MBTL1ALDH1A1 | |
| SCHEMBL8598193 | 0.82 | ELANE (0.39) | SMN1; SMN2HTTRECQLATML3MBTL1 | |
| SCHEMBL8603005 | 0.82 | NR1I2 (0.39) | — | |
| SCHEMBL8599287 | 0.81 | L3MBTL1 (0.48) | HTTRECQLPPOXL3MBTL1ALDH1A1 | |
| SCHEMBL8601232 | 0.81 | TLR8 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |