Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601269 | 0.80 | MIF (0.36) | MAPK1TSHRESR1LTA4H | |
| SCHEMBL11638205 | 0.75 | CTSK (0.47) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR | |
| SCHEMBL13290804 | 0.74 | TSHR (0.57) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR | |
| SCHEMBL3654423 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR | |
| SCHEMBL11634740 | 0.73 | CTSL (0.56) | SMN1; SMN2MAPK1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL1553456 | 0.71 | FOLH1 (0.51) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR | |
| SCHEMBL12487151 | 0.71 | LMNA (0.47) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR | |
| SCHEMBL388023 | 0.71 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR | |
| SCHEMBL7471348 | 0.70 | CNR1 (0.45) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR | |
| SCHEMBL11499291 | 0.70 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMAPK1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |