Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048962 | 0.90 | GPR174 (0.72) | GPR174MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL22388441 | 0.84 | GPR174 (1.00) | GPR174MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10338925 | 0.81 | GPR174 (0.58) | GPR174MEN1KMT2ALMNAMAPT | |
| SCHEMBL8657499 | 0.81 | NPC1 (0.70) | GPR174MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL12810424 | 0.78 | MAPT (0.61) | GPR174MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL8476280 | 0.78 | LMNA (0.70) | MEN1KMT2ALMNACYP1A2TDP1 | |
| SCHEMBL104013 | 0.77 | L3MBTL1 (0.63) | GPR174LMNAMAPTALDH1A1POLB | |
| SCHEMBL11057029 | 0.77 | GPR174 (0.55) | GPR174MEN1KMT2ALMNAMAPT | |
| SCHEMBL13611998 | 0.76 | MAPT (0.66) | GPR174MEN1KMT2ALMNATDP1 | |
| SCHEMBL10204609 | 0.76 | ALDH1A1 (0.56) | GPR174MEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712856-B1 | Sunscreens, cosmetic sunscreen compositions and use thereof | OREAL (FR) | 1998-01-28 | — | — | EP | disclosed |
| US-5587151-A | TOPICALLY APPLICABLE SUNSCREEN/COSMETIC COMPOSITIONS FOR ENHANCED PHOTOPROTECTION OF HUMAN SKIN AND/OR HAIR FROM DAMAGING EFFECTS OF SOLAR RADIATION | L'OREAL (FR) | 1996-12-24 | — | — | US | disclosed |
| EP-0712856-A1 | Sunscreens, cosmetic sunscreen compositions and use thereof | L'OREAL (FR) | 1996-05-22 | — | — | EP | disclosed |