Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598478 | 0.89 | AAK1 (0.32) | AAK1CHRNB2CHRNA4 | |
| SCHEMBL8598142 | 0.89 | CYP19A1 (0.38) | CYP11B1CYP11B2CYP19A1GRM5POLB | |
| SCHEMBL8600956 | 0.85 | PTAFR (0.40) | CYP11B1CYP11B2CYP19A1AAK1GRM5 | |
| SCHEMBL8602211 | 0.82 | ERN1 (0.33) | ERN1 | |
| SCHEMBL8602621 | 0.82 | SQOR (0.31) | — | |
| SCHEMBL8601156 | 0.82 | CYP2D6 (0.32) | CYP19A1 | |
| SCHEMBL8602104 | 0.81 | PTAFR (0.37) | CYP11B1CYP11B2CYP19A1MKNK1MKNK2 | |
| SCHEMBL8600165 | 0.81 | FGFR4 (0.36) | — | |
| SCHEMBL8604338 | 0.81 | CYP11B1 (0.42) | CYP11B1CYP11B2CYP19A1AAK1POLB | |
| SCHEMBL8597829 | 0.79 | CYP11B1 (0.38) | CYP11B1CYP11B2CYP19A1AAK1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |