Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598609 | 0.96 | PPOX (0.42) | PPOXMAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL8601522 | 0.85 | SCN9A (0.36) | PPOXMAPTLMNARAB9ANPC1 | |
| SCHEMBL8600440 | 0.84 | PPOX (0.50) | PPOXMAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL8599998 | 0.83 | LMNA (0.56) | PPOXMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8600411 | 0.82 | RORC (0.32) | GAA | |
| SCHEMBL8603600 | 0.82 | TDP1 (0.46) | MAPTALDH1A1TDP1TSHRHPGD | |
| SCHEMBL10550045 | 0.81 | LMNA (0.38) | PPOXMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8600473 | 0.81 | TDP1 (0.41) | PPOXMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8602405 | 0.81 | LMNA (0.40) | PPOXMAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL8599287 | 0.80 | L3MBTL1 (0.48) | PPOXMAPTLMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |