Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 7/20 | 0.41 |
| ▸ | HTR2C | P28335 | 10/20 | 0.38 |
| ▸ | HTR2B | P41595 | 8/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533072 | 0.86 | PPOX (0.43) | PPOXHTR2CHTR2BHTR2AADRA2A | |
| SCHEMBL8603158 | 0.84 | — | — | |
| SCHEMBL8599601 | 0.84 | — | — | |
| SCHEMBL8599604 | 0.84 | — | — | |
| SCHEMBL8602412 | 0.81 | PPOX (0.38) | PPOXHTR2C | |
| SCHEMBL8600619 | 0.79 | SMN1; SMN2 (0.42) | PPOXTSHR | |
| SCHEMBL4593568 | 0.79 | LMNA (0.41) | HTR2CHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL8599225 | 0.79 | PPOX (0.40) | PPOX | |
| SCHEMBL8599691 | 0.78 | LMNA (0.33) | PPOXHTR2CHTR2BHTR2A | |
| SCHEMBL8603005 | 0.78 | NR1I2 (0.39) | HTR2CHTR2AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |