Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603616 | 0.92 | SLC6A4 (0.47) | SLC6A4SLC6A2KDM4EPPARGPPARA | |
| SCHEMBL8602010 | 0.86 | SLC6A4 (0.46) | SLC6A4SLC6A2KDM4EPPARGPPARA | |
| SCHEMBL8604557 | 0.82 | SLC6A4 (0.45) | SLC6A4SLC6A2KDM4EGAAPPARG | |
| SCHEMBL8602034 | 0.78 | KMT2A (0.41) | SLC6A4SLC6A2PPARGPPARAKMT2A | |
| SCHEMBL8604548 | 0.77 | MMP8 (0.43) | SLC6A4SLC6A2KDM4EPPARGPPARA | |
| SCHEMBL9230541 | 0.75 | MTNR1A (0.48) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8603715 | 0.73 | SLC6A4 (0.39) | SLC6A4SLC6A2KDM4EPPARGPPARA | |
| SCHEMBL8601737 | 0.73 | GAA (0.48) | SLC6A4SLC6A2KDM4EGAAPPARG | |
| SCHEMBL8627326 | 0.73 | MTNR1A (0.48) | MTNR1AMTNR1BKDM4EKEAP1NFE2L2 | |
| SCHEMBL8627320 | 0.71 | MTNR1A (0.50) | MTNR1AMTNR1BCNR1CNR2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723493-A | PROSTAGLANDIN DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |