Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GALE | Q14376 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901582 | 1.00 | NR1I2 (0.44) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL9769754 | 0.88 | NR1I2 (0.41) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL9769677 | 0.84 | MAOA (0.40) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL8415850 | 0.83 | NR1I2 (0.41) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL4592760 | 0.82 | PGK1 (0.43) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL8878658 | 0.82 | ALOX5AP (0.39) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL8599602 | 0.80 | PPOX (0.45) | HTR2CNPC1MAOAGAAPPOX | |
| SCHEMBL14529596 | 0.79 | NR1I2 (0.67) | NR1I2ADRA2AADORA3ADRA2BADRA2C | |
| SCHEMBL9872059 | 0.77 | NPC1 (0.43) | HTR2AHTR2CNPC1MAOAGAA | |
| SCHEMBL8604315 | 0.77 | CSNK2A1 (0.49) | NPC1MAOAGAAPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200985-B | Pteridinone compound and preparation method and application thereof | 南开大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-113200985-A | Pteridinone compound and preparation method and application thereof | 南开大学 | 2021-08-03 | — | — | CN | disclosed |
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |