Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 8/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120934 | 0.76 | ACHE (0.56) | ACHEALDH1A1CYP1A2 | |
| SCHEMBL29120939 | 0.73 | ACHE (0.53) | ACHEALDH1A1CYP1A2BCHEGRIN1 | |
| SCHEMBL9584331 | 0.72 | ACHE (1.00) | ACHEBCHECHRM1EPHX2GRIN1 | |
| SCHEMBL17423119 | 0.71 | POLB (0.55) | ACHEALDH1A1BCHECHRM1EPHX2 | |
| SCHEMBL4266767 | 0.71 | ACHE (0.74) | ACHEBCHECHRM1EPHX2GRIN1 | |
| SCHEMBL7385584 | 0.67 | ACHE (0.51) | ACHEBCHECHRM1EPHX2POLB | |
| SCHEMBL31500251 | 0.66 | MAOA (0.52) | ACHEALDH1A1BCHECHRM1EPHX2 | |
| SCHEMBL7384830 | 0.65 | ACHE (0.49) | ACHEBCHECHRM1EPHX2POLB | |
| SCHEMBL10575185 | 0.65 | ACHE (0.49) | ACHEALDH1A1CYP1A2BCHECHRM1 | |
| SCHEMBL7388062 | 0.65 | SMYD3 (0.52) | ACHEALDH1A1BCHECHRM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |