Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31500251 | 0.93 | MAOA (0.52) | POLBMAOAMAOBNR4A2ESR1 | |
| SCHEMBL9709249 | 0.89 | MAOA (0.72) | POLBMAOAMAOBNR4A2ESR1 | |
| SCHEMBL31500224 | 0.85 | MAOA (0.58) | MAOAMAOBNR4A2MPOACHE | |
| SCHEMBL22791812 | 0.83 | LMNA (0.50) | POLBMAOAMAOBNR4A2ESR1 | |
| SCHEMBL11194565 | 0.83 | KDM4E (0.61) | POLBMPOACHECHRM1KMT2A | |
| SCHEMBL13737248 | 0.83 | DHODH (0.44) | POLBMAOAMAOBNR4A2ESR1 | |
| SCHEMBL28220511 | 0.81 | POLB (0.47) | POLBNR4A2ESR1ESR2MPO | |
| SCHEMBL31038657 | 0.79 | KDM4E (0.68) | POLBACHECHRM1KMT2AKDM4E | |
| SCHEMBL30603139 | 0.79 | KDM4E (0.68) | POLBACHECHRM1KMT2AKDM4E | |
| SCHEMBL2448633 | 0.79 | KDM4E (0.68) | POLBACHECHRM1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016005979-A1 | METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS IN HONEYBEES | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2016-01-14 | — | — | WO | disclosed |