Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.55 |
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11976615 | 0.86 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DALK | |
| SCHEMBL18858718 | 0.85 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DALK | |
| SCHEMBL1553465 | 0.81 | PDE4A (0.62) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11975861 | 0.81 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DALK | |
| SCHEMBL11977105 | 0.81 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DALK | |
| Hydrochloric Acid SCHEMBL8601366 | 0.80 | PDE4A (0.61) | SLC22A12PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20424758 | 0.78 | ALOX5 (0.51) | PDE4APDE4BPDE4CPDE4DALK | |
| SCHEMBL8601359 | 0.78 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DALK | |
| SCHEMBL16752184 | 0.77 | SLC22A12 (0.54) | SLC22A12PTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL4011279 | 0.77 | L3MBTL1 (0.69) | ALKL3MBTL1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |