SCHEMBL8604367

SCHEMBL8604367

CC(C)C(c1ccsc1)S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
ALDH1A1 P00352 1/20 0.35
GRIA4 P48058 2/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
DAO P14920 1/20 0.31
GRIA2 P42262 1/20 0.31
ADRB3 P13945 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8358478 0.81 ALOX5 (0.46) ALOX5GRIA4CHRNB2CHRNB4CHRNA3
SCHEMBL8356404 0.79 ALOX5 (0.45) ALOX5GRIA4CHRNB2CHRNB4CHRNA3
SCHEMBL8605601 0.74 ALOX5 (0.41) ALOX5GRIA4CHRNB2CHRNB4CHRNA3
SCHEMBL28240701 0.73 ALOX5 (0.39) ALOX5GRIA4CHRNB2CHRNB4CHRNA3
SCHEMBL3445147 0.73 ALOX5 (0.39) ALOX5GRIA4CHRNB2CHRNB4CHRNA3
SCHEMBL30295390 0.73 ALOX5 (0.47) ALOX5GRIA4CHRNB2CHRNB4CHRNA3
SCHEMBL4357847 0.72 ALDH1A1 (0.64) ALDH1A1KDM4EMAPTSMN1; SMN2NPSR1
SCHEMBL10777503 0.70 ALOX5 (0.37) ALOX5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL11506419 0.70 SRC (0.58) ALOX5CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL8354255 0.70 CHRNB2 (0.38) ALOX5GRIA4CHRNB2CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459255-B1 Method for suppression of electrification HITACHI LTD (JP) 1998-03-18 EP disclosed
US-5589270-A Processed substrate obtained by a process for effecting suppression of electrification HITACHI, LTD. (JP) 1996-12-31 US disclosed
US-5437893-A Method for suppression of electrification HITACHI, LTD (JP) 1995-08-01 US disclosed
US-5256454-A Method for suppression of electrification HITACHI, LTD. (JP) 1993-10-26 US disclosed