SCHEMBL860493

SCHEMBL860493

C=CC[C](CC=C)c1ccccc1C(C=C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.37
KDM4E B2RXH2 4/20 0.36
MAPT P10636 4/20 0.36
CYP3A4 P08684 4/20 0.36
ALOX15 P16050 3/20 0.36
ALDH1A1 P00352 2/20 0.33
XDH P47989 1/20 0.33
HPGD P15428 3/20 0.33
USP2 O75604 2/20 0.33
TP53 P04637 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5682092 0.78 MAPT (0.39) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL6278245 0.78 ALDH1A1 (0.49) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL9542306 0.75 KDM4E (0.41) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL29129651 0.75 CTSD (0.41) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL27432511 0.74 AKR1C3 (0.46) KDM4EMAPTCYP3A4ALOX15ALDH1A1
SCHEMBL8509766 0.74 CYP2C19 (0.36) CYP2C19MAPTCYP3A4ALDH1A1XDH
SCHEMBL3792769 0.73 AKR1C3 (0.44) KDM4EMAPTCYP3A4ALOX15ALDH1A1
SCHEMBL10762626 0.72 GABRA1 (0.43) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL8118870 0.71 XDH (0.45) CYP2C19KDM4EMAPTCYP3A4ALOX15
SCHEMBL28692019 0.70 ALDH1A1 (0.44) CYP2C19KDM4EMAPTCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9199504-B2 Encapsulated mordant particle dispersion and method of preparing EASTMAN KODAK COMPANY (US) 2015-12-01 US disclosed
EP-2097271-B1 IMAGE RECORDING ELEMENT COMPRISING ENCAPSULATED MORDANT PARTICLES EASTMAN KODAK CO (US) 2012-03-28 EP disclosed
US-20110003154-A1 ENCAPSULATED MORDANT PARTICLE DISPERSION AND METHOD OF PREPARING KODAK (NEAR EAST) INC. 2011-01-06 US disclosed
US-7847027-B2 Encapsulated mordant particle dispersion and method of preparing EASTMAN KODAK COMPANY (US) 2010-12-07 US disclosed
US-7833591-B2 Image recording element comprising encapsulated mordant particles EASTMAN KODAK COMPANY (US) 2010-11-16 US disclosed
EP-2097271-A1 IMAGE RECORDING ELEMENT COMPRISING ENCAPSULATED MORDANT PARTICLES EASTMAN KODAK COMPANY (US) 2009-09-09 EP disclosed
WO-2008082475-A1 IMAGE RECORDING ELEMENT COMPRISING ENCAPSULATED MORDANT PARTICLES EASTMAN KODAK COMPANY (US) 2008-07-10 WO disclosed
US-20080160228-A1 IMAGE RECORDING ELEMENT COMPRISING ENCAPSULATED MORDANT PARTICLES BANK OF AMERICA, N.A., AS AGENT 2008-07-03 US disclosed
US-20080161493-A1 ENCAPSULATED MORDANT PARTICLE DISPERSION AND METHOD OF PREPARING KODAK AMERICAS LTD. 2008-07-03 US disclosed