Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17304946 | 0.86 | SMN1; SMN2 (0.44) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL12765969 | 0.84 | MAPT (0.48) | ALDH1A1KDM4ETSHRMEN1GAA | |
| SCHEMBL15344884 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TSHRCYP3A4GAAHPGD | |
| SCHEMBL2091678 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4ETUBB1CYP1A2CYP3A4 | |
| SCHEMBL17616775 | 0.81 | ALDH1A1 (0.62) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL20327305 | 0.80 | ATM (0.53) | CA2ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8395 | 0.79 | PTGS2 (0.53) | KDM4ETUBB1CYP19A1CYP3A4ABCB1 | |
| SCHEMBL633798 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23187814 | 0.79 | PTGS1 (0.43) | ALDH1A1LDHACYP3A4MEN1GAA | |
| SCHEMBL23458348 | 0.79 | CA2 (0.48) | CA2ALDH1A1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3996 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300932-A1 | CYCLIC PEPTIDES TARGETING ALPHA-4-BETA-7 INTEGRIN | ZEALAND PHARMA A/S (DK) | 2021-09-30 | — | — | US | claimed |
| US-11072616-B2 | Cyclic peptides targeting alpha-4-beta-7 integrin | UNIVERSITE DE MONTREAL (CA) | 2021-07-27 | — | — | US | claimed |
| CN-106103463-B | Bridging type nucleosides and nucleotide | 国立大学法人大阪大学 | 2018-11-30 | — | — | CN | claimed |
| EP-3109254-B1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | UNIV OSAKA (JP) | 2018-04-11 | — | — | EP | claimed |
| CN-105152992-A | Cyclopiane tetracyclic diterpene analogue, method for synthesizing same and application of cyclopiane tetracyclic diterpene analogue | UNIV LANZHOU | 2015-12-16 | — | — | CN | claimed |
| US-9200006-B2 | Protease inhibitors | MEDIVIR AB (SE) | 2015-12-01 | — | — | US | claimed |
| US-8618286-B2 | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2013-12-31 | — | — | US | claimed |
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| US-8106043-B2 | Benzoxazines, benzothiazines, and related compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2012-01-31 | — | — | US | claimed |
| EP-1501812-B1 | PNA MONOMER AND PRECURSOR | PANAGENE INC (KR) | 2009-12-30 | — | — | EP | claimed |
| US-5234930-A | Treating psychological, cardiovascular, urogenital and respiratory disorders; diabetes, asthmas, sudden infant death syndrome | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | claimed |
| US-5120746-A | Inhibit gastric acid secretion | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | claimed |
| US-4643849-A | ANTIULCER, ANTISECRETORY AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-02-17 | — | — | US | claimed |
| US-4267340-A | BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | claimed |
| US-4246405-A | Method for preparation of β-lactam compound | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-01-20 | — | — | US | claimed |
| EP-0016136-A1 | INHIBITION BY PEPTIDES OF TOLERANCE TO AND DEPENDENCE ON MORPHINE | University of Illinois Foundation (US) | 1980-10-01 | — | — | EP | claimed |
| WO-1980000216-A1 | INHIBITION BY PEPTIDES OF TOLERANCE TO AND DEPENDENCE ON MORPHINE | UNIV ILLINOIS (US) | 1980-02-21 | — | — | WO | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | claimed |