Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374605 | 0.84 | MTNR1A (0.53) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL3105534 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL17933246 | 0.78 | NR3C2 (0.47) | MTNR1AMTNR1BCYP1A2TP53 | |
| SCHEMBL28758819 | 0.77 | UTS2R (0.46) | KDM4ESMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL7102909 | 0.74 | PTPN7 (0.42) | MTNR1AMTNR1BKDM4ESMN1; SMN2HPGD | |
| SCHEMBL11514183 | 0.73 | SIGMAR1 (0.47) | MTNR1AMTNR1BKDM4EALDH1A1KMT2A | |
| SCHEMBL8852613 | 0.73 | INSR (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL7012336 | 0.72 | BCHE (0.51) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1176872 | 0.72 | ESR1 (0.49) | MTNR1AMTNR1BKDM4ESMN1; SMN2HPGD | |
| SCHEMBL27277472 | 0.72 | CRHBP (0.47) | MTNR1AMTNR1BKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753290-A | VULCANIZED RUBBER LATEX | GLOBE MANUFACTURING CO. (US) | 1998-05-19 | — | — | US | disclosed |
| US-4221703-A | COPOLYESTERETHER, AMIDE-CONTAINING PHENOLIC ANTIOXIDANT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-09 | — | — | US | disclosed |
| US-4094857-A | Copolymerizable phenolic antioxidant | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-3957513-A | Method of free radical photography utilizing a short light flash for exposure | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1976-05-18 | — | — | US | disclosed |