SCHEMBL860540

SCHEMBL860540

CC(C)SSc1ccccn1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.64
EHMT1 Q9H9B1 1/20 0.64
APOBEC3G Q9HC16 1/20 0.64
HPGD P15428 4/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
HSD17B10 Q99714 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 6/20 0.37
MAPT P10636 4/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
USP2 O75604 1/20 0.37
GAA P10253 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195057 1.00 EHMT2 (0.64) EHMT2EHMT1APOBEC3GHPGDKMT2A
Phosphoric Acid SCHEMBL17592569 0.89 EHMT2 (0.52) EHMT2EHMT1APOBEC3GHPGDKMT2A
SCHEMBL1271372 0.88 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHPGDKMT2A
Hydrochloric Acid SCHEMBL3978581 0.86 EHMT2 (0.57) EHMT2EHMT1APOBEC3GHPGDKMT2A
SCHEMBL24599713 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHPGDKMT2A
SCHEMBL803314 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHPGDKMT2A
SCHEMBL15301017 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHPGDKMT2A
SCHEMBL16486465 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHPGDKMT2A
SCHEMBL16132722 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHPGDKMT2A
SCHEMBL26969574 0.84 EHMT2 (0.59) EHMT2EHMT1APOBEC3GHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3693391-B1 ANTI-CLL-1 ANTIBODIES AND IMMUNOCONJUGATES GENENTECH INC (US) 2024-08-21 EP claimed
EP-3693391-A1 ANTI-CLL-1 ANTIBODIES AND IMMUNOCONJUGATES Genentech, Inc. (US) 2020-08-12 EP claimed
US-20260132220-A1 Cysteine Engineered Antibodies and Conjugates GENENTECH, INC. (US) 2026-05-14 US disclosed
US-12492263-B2 Anti-HER2 antibodies and immunoconjugates GENENTECH, INC. (US) 2025-12-09 US disclosed
US-20250297011-A1 Anti-B7-H4 Antibodies and Immunoconjugates GENENTECH, INC. (US) 2025-09-25 US disclosed
US-12281165-B2 Anti-B7-H4 antibodies and immunoconjugates GENENTECH, INC. (US) 2025-04-22 US disclosed
EP-3693391-B1 ANTI-CLL-1 ANTIBODIES AND IMMUNOCONJUGATES GENENTECH INC (US) 2024-08-21 EP disclosed
US-20240239894-A1 THERAPEUTIC BINDING MOLECULES MEDIMMUNE LIMITED (GB) 2024-07-18 US disclosed
US-20240209425-A1 GENERATING CAPTURE PROBES FOR SPATIAL ANALYSIS 10X GENOMICS, INC. 2024-06-27 US disclosed
US-20240209425-A1 GENERATING CAPTURE PROBES FOR SPATIAL ANALYSIS 10X GENOMICS, INC. 2024-06-27 US disclosed
US-20240110909-A1 BIOANALYTICAL ANALYSIS OF SITE-SPECIFIC ANTIBODY DRUG CONJUGATES GENENTECH, INC. (US) 2024-04-04 US disclosed
WO-2012004008-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2012-01-12 WO disclosed
WO-2012004005-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2012-01-12 WO disclosed
WO-2012004006-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2012-01-12 WO disclosed
WO-2012004009-A1 CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2012-01-12 WO disclosed
US-20100094020-A1 POLYCATIONIZED PHOSPHOLIPID DERIVATIVES EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-04-15 US disclosed
US-20100021480-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME PEPTRON CO., LTD (KR) 2010-01-28 US disclosed
US-20080182815-A1 Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) UNIVERSITY OF SOUTH FLORIDA 2008-07-31 US disclosed
US-20080182815-A1 Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) UNIVERSITY OF SOUTH FLORIDA 2008-07-31 US disclosed
US-20080182815-A1 Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) UNIVERSITY OF SOUTH FLORIDA 2008-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492263-B2 Anti-HER2 antibodies and immunoconjugates ERBB2, EGFR, ERBB3 EHMT2 1031/4885EHMT1 2274/4885APOBEC3G 1092/4885
US-20080182815-A1 Act against several infective agents, and most notably Bacillus spp. and Staphylococcus spp., including infection caused by methicillin-resistant Staphylococcus aureus (MRSA) SQOR, TST, COASY EHMT2 3558/4885EHMT1 3574/4885APOBEC3G 2997/4885
US-20240110909-A1 BIOANALYTICAL ANALYSIS OF SITE-SPECIFIC ANTIBODY DRUG CONJUGATES GUSB, DNPEP, FUCA2 EHMT2 2562/4885EHMT1 3067/4885APOBEC3G 2110/4885
US-20100021480-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME SERPINA6, CSTB, PLG EHMT2 4036/4885EHMT1 4303/4885APOBEC3G 3337/4885
US-20240239894-A1 THERAPEUTIC BINDING MOLECULES EPCAM, IGSF11, FCGR3B EHMT2 1645/4885EHMT1 2171/4885APOBEC3G 1464/4885
US-20250297011-A1 Anti-B7-H4 Antibodies and Immunoconjugates CD44, NECTIN4, H1-4 EHMT2 64/4885EHMT1 86/4885APOBEC3G 2045/4885
US-20260132220-A1 Cysteine Engineered Antibodies and Conjugates IGLV6-57, GCLC, QPCTL EHMT2 472/4885EHMT1 741/4885APOBEC3G 559/4885
US-20100094020-A1 POLYCATIONIZED PHOSPHOLIPID DERIVATIVES PHOSPHO1, PLTP, PTDSS2 EHMT2 2072/4885EHMT1 2588/4885APOBEC3G 2224/4885
US-12281165-B2 Anti-B7-H4 antibodies and immunoconjugates CD44, NECTIN4, H1-4 EHMT2 64/4885EHMT1 86/4885APOBEC3G 2045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.