Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565949 | 0.82 | FDPS (0.33) | FDPS | |
| SCHEMBL10371246 | 0.78 | — | — | |
| SCHEMBL1612949 | 0.77 | TSHR (0.35) | FDPS | |
| SCHEMBL8706 | 0.77 | — | — | |
| SCHEMBL10285142 | 0.77 | TSHR (0.35) | FDPS | |
| SCHEMBL2565897 | 0.77 | OPRM1 (0.33) | FDPS | |
| SCHEMBL2565496 | 0.77 | FDPS (0.31) | FDPS | |
| SCHEMBL5692103 | 0.72 | GABRR1 (0.33) | — | |
| SCHEMBL10367595 | 0.72 | KDM4E (0.32) | — | |
| SCHEMBL5949130 | 0.72 | DNM1 (0.38) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047278-A1 | Novel Combinational Use of Sulfonamide Compound | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1859793-A1 | NOVEL COMBINATIONAL USE OF SULFONAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-11-28 | — | — | EP | disclosed |
| EP-0889362-B1 | Photopolymerizable composition and dry film resist | SHOWA DENKO KK (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6033829-A | THERMOPLASTIC COPOLYMER OF AN ALPHA, BETA-UNSATURATED CARBOXYL GROUP-CONTAINING MONOMERS AND ANOTHER MONOMER; A CROSSLINKING MONOMER; AND A POLYMERIZATION INITIATOR COMPRISING A QUATERNARY BORON SALT AND A SENSITIZING DYE | SHOWA DENKO K.K. (JP) | 2000-03-07 | — | — | US | disclosed |
| US-5932574-A | ANTICANCER AGENT | ZENECA LIMITED (GB) | 1999-08-03 | — | — | US | disclosed |
| EP-0889362-A1 | Photopolymerizable composition and dry film resist | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-01-07 | — | — | EP | disclosed |
| US-5770599-A | RECEPTOR TYROSINE KINASE INHIBITORS including 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(2-morpholinoethoxy)quinazoline (gefitinib) | ZENECA LIMITED (GB) | 1998-06-23 | — | — | US | disclosed |
| EP-0824525-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0823900-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996033980-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-10-31 | — | — | WO | disclosed |
| WO-1996033977-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-10-31 | — | — | WO | disclosed |
| US-4536512-A | 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2,3-dihydro-1H-pyrrolizine-1-alkanoic or carboxylic acids and use thereof as anti-inflammatory and analgesic agents | MERCK & CO., INC. (US) | 1985-08-20 | — | — | US | disclosed |
| US-4533671-A | 5-(2,3-Dihydro-1H-pyrrolizin-5-oyl)-2-alkanoic or carboxylic acids and analogs as anti-inflammatory and analgesic agents | MERCK & CO., INC. (US) | 1985-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047278-A1 | Novel Combinational Use of Sulfonamide Compound | EGFR, KIT, ERBB2 | FDPS 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.