Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 5/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557980 | 0.88 | LMNA (0.41) | ALDH1A1MAPT | |
| SCHEMBL8608435 | 0.78 | GAA (0.31) | — | |
| SCHEMBL8607601 | 0.78 | HPGD (0.40) | ALDH1A1MAPTCTSC | |
| SCHEMBL8609001 | 0.76 | TSHR (0.37) | POLBALDH1A1MAPT | |
| SCHEMBL8606555 | 0.76 | LMNA (0.43) | ALDH1A1MAPT | |
| SCHEMBL8195622 | 0.75 | ALDH1A1 (0.35) | POLBALDH1A1MAPT | |
| SCHEMBL8608727 | 0.74 | NR1I2 (0.39) | CTSC | |
| SCHEMBL8609476 | 0.74 | DPP4 (0.36) | CTSC | |
| SCHEMBL29355315 | 0.74 | F10 (0.37) | ALDH1A1 | |
| SCHEMBL8606438 | 0.74 | SLC6A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496630-B1 | 2-Cyano-1,3-dione herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-07 | — | — | EP | claimed |
| EP-0496630-A1 | 2-Cyano-1,3-dione herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-07-29 | — | — | EP | claimed |
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| EP-0496630-A1 | 2-Cyano-1,3-dione herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-07-29 | — | — | EP | disclosed |