Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592465 | 0.82 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL12701205 | 0.82 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL25343847 | 0.82 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL31729407 | 0.81 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL21349700 | 0.81 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL29678780 | 0.81 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL31729133 | 0.81 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL110643 | 0.81 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1ABL1GAA | |
| SCHEMBL8602337 | 0.79 | CASP1 (0.41) | KDM4ESMN1; SMN2PDK2GAAMEN1 | |
| SCHEMBL8606559 | 0.77 | AKR1C2 (0.48) | KDM4ESMN1; SMN2ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828713-A2 | PYRIDINE-MICROBICIDES | CIBA-GEIGY AG (CH) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037472-A2 | PYRIDINE-MICROBICIDES | NOVARTIS AG (CH) | 1996-11-28 | — | — | WO | disclosed |