Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 3/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606612 | 0.87 | LMNA (0.38) | LMNABCAT2TYK2JAK1JAK2 | |
| SCHEMBL8763780 | 0.83 | BCAT2 (0.39) | LMNABCAT2TYK2JAK1JAK2 | |
| SCHEMBL8493474 | 0.78 | TSHR (0.37) | LMNAPOLBSMN1; SMN2 | |
| SCHEMBL8492662 | 0.78 | LMNA (0.43) | LMNABCAT2TYK2JAK1JAK2 | |
| SCHEMBL8891000 | 0.75 | NR3C1 (0.38) | LMNABCAT2SMN1; SMN2GPBAR1 | |
| SCHEMBL8891900 | 0.73 | TSHR (0.39) | LMNAPOLBSMN1; SMN2 | |
| SCHEMBL8762917 | 0.73 | WDR5 (0.37) | LMNAPOLB | |
| SCHEMBL8890411 | 0.72 | TSHR (0.34) | LMNAPOLBSMN1; SMN2 | |
| SCHEMBL4321077 | 0.70 | BCAT2 (0.59) | LMNABCAT2MEN1NPC1RAB9A | |
| SCHEMBL8608708 | 0.70 | LMNA (0.38) | LMNABCAT2TYK2JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |