Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605894 | 0.84 | L3MBTL1 (0.39) | KDM4EKITGAAPOLBHSP90AA1 | |
| SCHEMBL8608572 | 0.72 | ALDH1A1 (0.40) | KDM4EGAAPOLBCYP3A4ALDH1A1 | |
| SCHEMBL7789860 | 0.72 | ALDH1A1 (0.41) | KDM4ESLC6A4GAAPOLBCYP3A4 | |
| SCHEMBL8604623 | 0.71 | ALDH1A1 (0.36) | KDM4EKITPOLBMAOAMAOB | |
| SCHEMBL8605524 | 0.71 | DRD2 (0.39) | KDM4ESLC6A4KITPOLBALDH1A1 | |
| SCHEMBL13934564 | 0.69 | PDE10A (0.41) | KDM4EGAAALDH1A1MAPK1 | |
| SCHEMBL8606451 | 0.68 | PPARA (0.34) | KDM4EKITPOLBHSP90AA1CYP3A4 | |
| SCHEMBL8607593 | 0.68 | EGLN2 (0.36) | KITPOLBCYP19A1 | |
| SCHEMBL8607084 | 0.68 | SCN5A (0.42) | KDM4EGAAPOLBALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL31728514 | 0.68 | PDE10A (0.40) | KDM4EGAAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753665-A | TRIAZOLOPYRIMIDINES, NERVOUS SYSTEM DISORDERS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-05-19 | — | — | US | claimed |
| US-5753665-A | TRIAZOLOPYRIMIDINES, NERVOUS SYSTEM DISORDERS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-05-19 | — | — | US | disclosed |