Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608578 | 0.88 | ABCB11 (0.44) | ABCB11PTGS2CYP2C9CYP2C19HTT | |
| SCHEMBL10881348 | 0.79 | ABCB11 (0.41) | ABCB11PTGS2CYP2C9CYP2C19HTT | |
| SCHEMBL11085390 | 0.77 | THRB (0.39) | ABCB11PTGS2CYP2C9CYP2C19HTT | |
| SCHEMBL7685136 | 0.77 | PTGS2 (0.53) | ABCB11PTGS2HTTSRD5A2TSHR | |
| SCHEMBL7684797 | 0.72 | PTGS2 (0.46) | ABCB11PTGS2HTTTSHRALDH1A1 | |
| SCHEMBL7676873 | 0.72 | HTT (0.44) | ABCB11PTGS2CYP2C9CYP2C19HTT | |
| SCHEMBL7683947 | 0.69 | PTGS2 (0.50) | ABCB11PTGS2HTTTSHRALDH1A1 | |
| SCHEMBL10965792 | 0.68 | KMT2A (0.44) | TSHRALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL16075922 | 0.68 | POLB (0.58) | CYP2C9CYP2C19LMNAPOLBKMT2A | |
| SCHEMBL7711076 | 0.68 | POLB (0.58) | CYP2C9CYP2C19LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |