Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730488 | 0.83 | ALOX5 (0.54) | ALOX5EPHX2 | |
| SCHEMBL8610041 | 0.81 | ALOX5 (0.51) | ALOX5NPC1RAB9AEPHX2ALDH1A1 | |
| SCHEMBL8309228 | 0.81 | ALOX5 (0.51) | ALOX5NPC1RAB9AEPHX2ALDH1A1 | |
| SCHEMBL8309230 | 0.81 | ALOX5 (0.51) | ALOX5NPC1RAB9AEPHX2ALDH1A1 | |
| SCHEMBL8307138 | 0.80 | NPC1 (0.48) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8303980 | 0.80 | NPC1 (0.48) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8941747 | 0.79 | ALOX5 (0.53) | ALOX5EPHX2 | |
| SCHEMBL8609455 | 0.76 | NPC1 (0.43) | ALOX5NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4729170 | 0.75 | NPC1 (0.45) | ALOX5NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8609409 | 0.75 | NPC1 (0.45) | ALOX5NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |