Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DCK | P27707 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303628 | 0.79 | ALOX5AP (0.38) | ALOX5APFEN1SMN1; SMN2ALDH1A1AR | |
| SCHEMBL8303630 | 0.79 | ALOX5AP (0.38) | ALOX5APFEN1SMN1; SMN2ALDH1A1AR | |
| SCHEMBL8610030 | 0.76 | ATM (0.44) | ATMSMN1; SMN2ALDH1A1HPGDIMPDH2 | |
| SCHEMBL27907032 | 0.72 | ALDH1A1 (0.51) | ATMSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1548278 | 0.70 | ALDH1A1 (0.54) | ATMSMN1; SMN2ALDH1A1HPGDIMPDH2 | |
| SCHEMBL13885660 | 0.70 | ALDH1A1 (0.51) | ATMSMN1; SMN2ALDH1A1HPGDAR | |
| SCHEMBL8539615 | 0.69 | ATM (0.52) | ATMSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8539618 | 0.69 | ATM (0.52) | ATMSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL34460861 | 0.68 | TSHR (0.50) | ATMSMN1; SMN2ALDH1A1HPGDIMPDH2 | |
| SCHEMBL31158568 | 0.68 | TSHR (0.50) | ATMSMN1; SMN2ALDH1A1HPGDIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |