Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610045 | 0.91 | SLC9A1 (0.48) | SLC9A1TDP1KCNH2F2PRSS1 | |
| SCHEMBL9018731 | 0.84 | SLC9A1 (0.42) | SLC9A1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL9018676 | 0.82 | SLC9A1 (0.49) | SLC9A1KCNH2HTR3EHTR3BHTR3A | |
| SCHEMBL9018725 | 0.82 | SLC9A1 (0.49) | SLC9A1KCNH2HTR3EHTR3BHTR3A | |
| SCHEMBL9018712 | 0.81 | SLC9A1 (0.47) | SLC9A1TDP1F2PRSS1PRSS2 | |
| SCHEMBL9018710 | 0.78 | SLC9A1 (0.54) | SLC9A1KCNH2 | |
| SCHEMBL8653264 | 0.77 | SLC9A1 (0.41) | SLC9A1ALDH1A1CYP3A4ALOX15TSHR | |
| SCHEMBL9018719 | 0.76 | AKR1B1 (0.46) | SLC9A1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL27386925 | 0.76 | TDP1 (0.47) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL8610762 | 0.75 | SLC9A1 (0.47) | SLC9A1TDP1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |