Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018718 | 0.93 | SLC9A1 (0.41) | TDP1SLC9A1MEN1KMT2AMITF | |
| SCHEMBL8612597 | 0.85 | CFTR (0.48) | TDP1SIRT6SLC9A1MEN1KMT2A | |
| SCHEMBL8608691 | 0.82 | SLC9A1 (0.40) | TDP1SIRT6SLC9A1MEN1KMT2A | |
| SCHEMBL8610762 | 0.82 | SLC9A1 (0.47) | TDP1SIRT6SLC9A1MEN1KMT2A | |
| SCHEMBL8610122 | 0.80 | SLC9A1 (0.40) | SLC9A1MRGPRX4 | |
| SCHEMBL8610216 | 0.80 | MRGPRX4 (0.39) | SLC9A1KMT2AALDH1A1MRGPRX4 | |
| SCHEMBL8614188 | 0.78 | MRGPRX4 (0.40) | SLC9A1KMT2AMRGPRX4 | |
| SCHEMBL8614095 | 0.78 | MRGPRX4 (0.38) | SLC9A1MRGPRX4 | |
| SCHEMBL7688039 | 0.78 | MEN1 (0.45) | TDP1SIRT6MEN1KMT2AMITF | |
| SCHEMBL8611570 | 0.78 | CFTR (0.40) | KMT2AALDH1A1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |