Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018694 | 0.94 | SLC9A1 (0.44) | SLC9A1 | |
| SCHEMBL2325954 | 0.87 | NOTUM (0.46) | MRGPRX4CFTRNOTUM | |
| SCHEMBL8610216 | 0.85 | MRGPRX4 (0.39) | SLC9A1MRGPRX4CFTR | |
| SCHEMBL8613343 | 0.84 | CFTR (0.53) | SLC9A1CFTR | |
| SCHEMBL8614095 | 0.83 | MRGPRX4 (0.38) | SLC9A1MRGPRX4CFTR | |
| SCHEMBL8614188 | 0.83 | MRGPRX4 (0.40) | SLC9A1MRGPRX4CFTR | |
| SCHEMBL8611570 | 0.82 | CFTR (0.40) | MRGPRX4CFTR | |
| SCHEMBL8612520 | 0.82 | SLC9A1 (0.40) | SLC9A1MRGPRX4 | |
| SCHEMBL8612355 | 0.80 | TDP1 (0.47) | SLC9A1MRGPRX4 | |
| SCHEMBL8612846 | 0.80 | MRGPRX4 (0.38) | MRGPRX4CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |