Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018732 | 0.92 | FFAR4 (0.40) | ABL1SLC9A1BRAFKMT2ACHEK1 | |
| SCHEMBL8611570 | 0.88 | CFTR (0.40) | MRGPRX4ABL1CFTRALDH1A1KMT2A | |
| SCHEMBL17478821 | 0.87 | ABL1 (0.45) | MRGPRX4ABL1CFTRBRAFALDH1A1 | |
| SCHEMBL8610122 | 0.85 | SLC9A1 (0.40) | MRGPRX4CFTRSLC9A1 | |
| SCHEMBL8611439 | 0.84 | CFTR (0.53) | MRGPRX4CFTRSLC9A1PDK2KDM4E | |
| SCHEMBL8614188 | 0.83 | MRGPRX4 (0.40) | MRGPRX4CFTRSLC9A1KMT2AKDM4E | |
| SCHEMBL8614095 | 0.83 | MRGPRX4 (0.38) | MRGPRX4ABL1CFTRSLC9A1CHEK1 | |
| SCHEMBL8612520 | 0.82 | SLC9A1 (0.40) | MRGPRX4SLC9A1 | |
| SCHEMBL9018666 | 0.81 | PIM1 (0.40) | SLC9A1KMT2ACHEK1FFAR1FFAR4 | |
| SCHEMBL9018694 | 0.80 | SLC9A1 (0.44) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |