Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614791 | 0.98 | MAOA (0.59) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL8612168 | 0.87 | MAOA (0.57) | MAOACHRM2SIGMAR1HRH4HRH3 | |
| SCHEMBL8614361 | 0.84 | MAOA (0.67) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL8612202 | 0.84 | MAOA (0.67) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL8613882 | 0.84 | MAOA (0.67) | MAOACHRM2SIGMAR1HDAC3HDAC1 | |
| Bromide SCHEMBL10730576 | 0.83 | MAOA (0.77) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| Bromide SCHEMBL28412992 | 0.83 | MAOA (0.77) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| Bromide SCHEMBL7032019 | 0.83 | MAOA (0.77) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| Bromide SCHEMBL5549665 | 0.83 | MAOA (0.77) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| Bromide SCHEMBL11269703 | 0.83 | MAOA (0.77) | MAOACHRM2SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |