Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.48 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609467 | 0.89 | CA2 (0.44) | SLC9A1CYP46A1ALDH1A1LMNAKDM4E | |
| SCHEMBL8610651 | 0.88 | SLC9A1 (0.48) | SLC9A1CYP46A1ALDH1A1LMNAKDM4E | |
| SCHEMBL8610225 | 0.83 | SLC9A1 (0.63) | SLC9A1CYP46A1ALDH1A1LMNAKDM4E | |
| SCHEMBL8700512 | 0.81 | CFTR (0.45) | ALDH1A1LMNAMAPK1HSD17B10PTGS2 | |
| SCHEMBL8609124 | 0.81 | SLC9A1 (0.51) | SLC9A1CYP46A1ALDH1A1LMNAKDM4E | |
| SCHEMBL8610220 | 0.81 | SLC9A1 (0.51) | SLC9A1CYP46A1ALDH1A1LMNAKDM4E | |
| SCHEMBL8608779 | 0.81 | SLC9A1 (0.51) | SLC9A1CYP46A1ALDH1A1LMNAKDM4E | |
| SCHEMBL8574336 | 0.80 | ALDH1A1 (0.37) | SLC9A1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL8533480 | 0.80 | SLC9A1 (0.73) | SLC9A1 | |
| SCHEMBL8610266 | 0.80 | SLC9A1 (0.50) | SLC9A1CYP46A1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |