SCHEMBL8610319

SCHEMBL8610319

CCOCCCCCCCC(O)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
USP2 O75604 1/20 0.35
HTT P42858 2/20 0.34
ALDH1A1 P00352 1/20 0.33
CETP P11597 1/20 0.32
PLA2G2C Q5R387 2/20 0.32
SPHK1 Q9NYA1 1/20 0.32
PKM P14618 1/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
LPAR5 Q9H1C0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8203331 1.00 CES2 (0.38) CES2CES1USP2HTTALDH1A1
SCHEMBL8610321 1.00 CES2 (0.38) CES2CES1USP2HTTALDH1A1
SCHEMBL8054036 1.00 CES2 (0.38) CES2CES1USP2HTTALDH1A1
SCHEMBL8082918 1.00 CES2 (0.38) CES2CES1USP2HTTALDH1A1
SCHEMBL7754281 0.98 CES2 (0.35) CES2CES1USP2HTTALDH1A1
SCHEMBL7754285 0.98 CES2 (0.35) CES2CES1USP2HTTALDH1A1
SCHEMBL7634968 0.92 ALDH1A1 (0.36) CES2CES1ALDH1A1CETPPKM
SCHEMBL7754277 0.92 ALDH1A1 (0.36) CES2CES1ALDH1A1CETPPKM
SCHEMBL9435364 0.87 CES1 (0.41) CES2CES1USP2HTTALDH1A1
SCHEMBL7750647 0.85 USP2 (0.39) CES2CES1USP2HTTCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0497297-B1 Liquid crystal compound and liquid crystal display device MITSUBISHI GAS CHEMICAL CO (JP) 1998-04-08 EP disclosed
EP-0559088-B1 Dioxane type liquid crystal substance MITSUBISHI GAS CHEMICAL CO (JP) 1996-05-15 EP disclosed
US-5482651-A ANTIFERROELECTRIC MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1996-01-09 US disclosed
US-5364560-A Liquid crystal compound and liquid crystal display device MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1994-11-15 US disclosed
EP-0484849-B1 Optically active alcohol, process for producing same and liquid crystal compound using same MITSUBISHI GAS CHEMICAL CO (JP) 1994-08-31 EP disclosed
US-5264150-A Fluorinated, ether aromatic ester compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-11-23 US disclosed
EP-0559088-A1 Dioxane type liquid crystal substance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-09-08 EP disclosed
EP-0497297-A2 Liquid crystal compound and liquid crystal display device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-08-05 EP disclosed
EP-0484849-A1 Optically active alcohol, process for producing same and liquid crystal compound using same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-05-13 EP disclosed