SCHEMBL861056

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL861057	1.00	DPP4 (0.54)	DPP4DRD2DRD3TRPV4SIGMAR1
	SCHEMBL2598154	1.00	DPP4 (0.54)	DPP4DRD2DRD3TRPV4SIGMAR1
	SCHEMBL2598155	1.00	DPP4 (0.54)	DPP4DRD2DRD3TRPV4SIGMAR1
	SCHEMBL860675	0.91	DRD2 (0.55)	DPP4DRD2DRD3TRPV4
	SCHEMBL860674	0.91	DRD2 (0.55)	DPP4DRD2DRD3TRPV4
	SCHEMBL2598134	0.91	DRD2 (0.55)	DPP4DRD2DRD3TRPV4
	SCHEMBL2598133	0.91	DRD2 (0.55)	DPP4DRD2DRD3TRPV4
	SCHEMBL861651	0.89	DPP4 (0.46)	DPP4DRD2DRD3SIGMAR1ALDH1A1
	SCHEMBL861215	0.89	DPP4 (0.46)	DPP4DRD2DRD3SIGMAR1ALDH1A1
	SCHEMBL861650	0.89	DPP4 (0.46)	DPP4DRD2DRD3SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.